NOX5-IN-2 (Compound 17) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.70 µM. NOX5-IN-2 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 1.8 µM). NOX5-IN-2 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation[1].
Molecular Weight:
394.84
Formula:
C18H11ClN6OS
Target:
NADPH Oxidase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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