VNRX-9945 is a potent, broadly and orally active HBV CAM (capsid assembly modulator) with an EC50 of 2.6 nM. VNRX-9945 exhibits excellent and broad antiviral activity against multiple HBV genotypes in vitro, along with favorable pharmacokinetic profiles across multiple species. VNRX-9945 demonstrates robust antiviral efficacy in the adeno-associated virus mice models of HBV (AAV-HBV) infection[1].
Molecular Weight:
429.48
Purity:
99.46
CAS Number:
[2396680-45-6]
Formula:
C23H28FN3O4
Target:
HBV
Application Notes:
MCE Product type: Reference compound
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