POLRMT-IN-2 is a potent POLRMT inhibitor. POLRMT-IN-2 exhibits strong antiproliferative activity in MOLM-13 cells, with an IC50 of 1.01 µM. POLRMT-IN-2 disrupts mitochondrial function and induces apoptosis in MOLM-13cells. POLRMT-IN-2 can be used for the study of acute myeloid leukemia(AML)[1].
Molecular Weight:
576.64
Formula:
C34H32N4O5
Target:
Apoptosis,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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