PROTAC HBeAg degrader-1 is a PROTAC targeting degradation agent for HBeAg. PROTAC HBeAg degrader-1 recruits the VHL E3 ligase but degrades HBV protein HBeAg through VHL-independent mechanism. PROTAC HBeAg degrader-1 decreases levels of secreted and intracellular HBeAg. PROTAC HBeAg degrader-1 can be used for the research of hepatitis B virus (HBV)[1]. (Structure Note: Pink: HBeAg ligand (HY-174857), Blue: VHL Ligand (HY-125845), Black: linker, E3-linker (HY-135045))
Molecular Weight:
990.60
Formula:
C48H57ClFN9O7S2
Target:
HBV,PROTACs
Application Notes:
MCE Product type: Reference compound
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