AZ12943203 (Compound 13e) is a GSK-3 PET radioligand with a Kd of 2.94 nM. AZ12943203 has a significant inhibitory potency toward GSK-3beta (IC50 : 4.44 nM), and can specifically bind to GSK-3-rich regions of the rodent brain. AZ12943203 can be used for neurodegenerative diseases imaging, particularly Alzheimers disease[1].
Molecular Weight:
493.58
Formula:
C26H32FN7O2
Target:
Biochemical Assay Reagents,GSK-3
Application Notes:
MCE Product type: Reference compound1
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