JAK3-IN-18, CAS [[2914873-59-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-174999
Supplier Catalog Number:
HY-174999
Alternative Catalog Number:
MCE-HY-174999-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
JAK3-IN-18 is an orally active JAK3 and TEC inhibitor, with IC50s of 0.5391 nM and 12.40 nM, respectively. JAK3-IN-18 demonstrates outstanding selectivity over AK1, AK2, and TYk2, with selectivity ratios exceeding 10,000-fold. JAK3-IN-18 demonstrates excellent therapeutic efficacy in the experimental autoimmune encephalomyelitis (EAE) mouse model. JAK3-IN-18 can be used for the study of multiple sclerosis[1].
Molecular Weight:
337.35
CAS Number:
[2914873-59-7]
Formula:
C18H16FN5O
Target:
JAK,Tyrosinase
Application Notes:
MCE Product type: Reference compound
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