VEGFR-2-IN-70 is a potent VEGFR-2 inhibitor with an IC50 of 18.04 nM. VEGFR-2-IN-70 exhibits cytotoxicity against A549 and MCF-7 cancer cells with IC50 values of 0.43 µM and 3.8 µM, respectively. VEGFR-2-IN-70 induces G1 cell cycle arrest and apoptosis in lung cancer cells. VEGFR-2-IN-70 is useful in cancer research[1].
Molecular Weight:
440.91
Formula:
C20H17ClN6O2S
Target:
Apoptosis,Bcl-2 Family,Caspase,MDM-2/p53,VEGFR
Application Notes:
MCE Product type: Reference compound
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