QNX-10 is a fatty acid synthase (FASN) inhibitor (IC50 = 0.7 µM) with anticancer activity. QNX-10 exhibits potent FASN inhibition and cytotoxicity against colorectal and breast cancer cells. QNX-10 induces apoptosis and cell cycle arrest in S phase by upregulating the pro-apoptotic protein Bax and downregulating the anti-apoptotic protein Bcl-xL. QNX-10 can be used to investigate anticancer therapies targeting FASN enzymes[1].
Molecular Weight:
434.46
Formula:
C24H23FN4O3
Target:
Apoptosis,Bcl-2 Family,Fatty Acid Synthase (FASN)
Application Notes:
MCE Product type: Reference compound
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