Rosuvastatin-d6, CAS [[2070009-40-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-17504AS1
Supplier Catalog Number:
HY-17504AS1
Alternative Catalog Number:
MCE-HY-17504AS1-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
ZD 4522-d6
Rosuvastatin-d6 (ZD 4522-d6) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
