(3S,5R)-Rosuvastatin, CAS [[1242184-42-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-17504D
Supplier Catalog Number:
HY-17504D
Alternative Catalog Number:
MCE-HY-17504D-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM[2]. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[3].
