Ganglioside GT1b (bovine) (trisodium) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175073
Supplier Catalog Number:
HY-175073
Alternative Catalog Number:
MCE-HY-175073-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Ganglioside GT1b bovine trisodium is a trisialic acid ganglioside. Ganglioside GT1b bovine trisodium binds to botulinum toxin type A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 µM, respectively. Ganglioside GT1b bovine trisodium acts as a TLR2 agonist, leading to microglial activation, increased expression of pro-inflammatory factors, and increased pain sensitivity in spinal microglia. Ganglioside GT1b bovine trisodium also reduces the production of IL-6, IL-10, IgG, IgM, and IgA in human peripheral blood mononuclear cells (PBMCs). Ganglioside GT1b bovine trisodium increases extracellular glutamate levels in neural cell models. Ganglioside GT1b bovine trisodium has potential applications in research on immune system diseases and nervous system diseases[1][2][3][4][5].
Molecular Weight:
2195.28
Formula:
C95H162N5Na3O47
Target:
Interleukin Related,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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