Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) µM[2]. Clarithromycin significantly inhibits the HERG potassium current[3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K[4].
Molecular Weight:
747.95
Purity:
99.90
CAS Number:
[81103-11-9]
Formula:
C38H69NO13
Target:
Antibiotic,Autophagy,Bacterial,Cytochrome P450
Application Notes:
MCE Product type: Reference compound1
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