Deracoxib (SC 046, SC 59046), an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas[1][2][3][4][5].
Molecular Weight:
397.37
Purity:
99.65
CAS Number:
[169590-41-4]
Formula:
C17H14F3N3O3S
Target:
Apoptosis,COX
Application Notes:
MCE Product type: Reference compound1
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