Adenosine receptor antagonist 6, CAS [[2913578-04-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175195
Supplier Catalog Number:
HY-175195
Alternative Catalog Number:
MCE-HY-175195-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Adenosine receptor antagonist 6 is an orally active and selective A2A adenosine receptor (A2AAR) antagonist, with a Ki of 19.18 nM. Adenosine receptor antagonist 6 inhibits 5-N-ethylcarboxamide adenosine (NECA) (HY-103173)-mediated cAMP production (IC50 = 0.089 µM) and immunosuppression, while promoting IL-2 and IFN-gamma secretion. Adenosine receptor antagonist 6 abolishes the immunosuppressive effects of adenosine on T-cell activation and cytokine release. Adenosine receptor antagonist 6 inhibits tumor growth in a CT26/MC38 xenograft model. Adenosine receptor antagonist 6 can be used for the study of colon cancer[1].
Molecular Weight:
332.36
CAS Number:
[2913578-04-6]
Formula:
C18H16N6O
Target:
Adenosine Receptor,Cytochrome P450,IFNAR,Interleukin Related
Application Notes:
MCE Product type: Reference compound
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