MT-228 (BPN-0026709) is a selective and blood-brain barrier permeable non-muscle myosin II inhibitor. MT-228 markedly improves tolerability by selectively targeting NMIIB (KI = 1.5 µM) over CMII (KI = 17 µM), and the sequence of SmMll MD is 83.6% identical to that of NMllB. MT-228 shows long-lasting efficacy in animal models of stimulant use disorder[1].
Molecular Weight:
337.37
Purity:
99.9
CAS Number:
[2404652-24-8]
Formula:
C19H19N3O3
Target:
Myosin
Application Notes:
MCE Product type: Reference compound
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