MST3-IN-1 is a selective and orally active MST3 inhibitor, with an IC50 of 122.4 nM. MST3-IN-1 shows antiproliferative activity against HepG2 cell. MST3-IN-1 effectively induces apoptosis in HepG2 cells, and halts the cell cycle at the G2/M transition. MST3-IN-1 significantly suppressed tumor growth in HepG2 xenograft mice. MST3-IN-1 can be used for the study of liver cancer[1].
Molecular Weight:
547.52
CAS Number:
[3095435-97-2]
Formula:
C25H21F4N5O3S
Target:
Apoptosis,Bcl-2 Family,Caspase,Hippo (MST)
Application Notes:
MCE Product type: Reference compound
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