ST171 is a bitopic 5-HT1AR agonist with an Ki of 0.41 nM. ST171 selectively activates Gi/o signaling pathway and inhibits 5-HT1AR-mediated cAMP accumulation without Gs activation and marginal beta-arrestin recruitment. T171 reduces hypersensitivity in chronic neuropathic and inflammatory pain mice model. ST171 can be used for pain research[1].
Molecular Weight:
372.41
Purity:
99.30
Formula:
C20H24N2O5
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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