PROTAC BRD4 Degrader-38 is a BRD4 PROTAC degrader with DC50s of 86 and 106 nM for the short and long isoforms of BRD4, respectively. PROTAC BRD4 Degrader-38 significantly induces the degradation of BRD4 by covalently engaging C232 of E3 ligase TRIM28[1].Pink: BRD4 ligand (HY-78695), Blue: E3 ligase ligand (HY-203082), Black: linker (HY-40172)
Molecular Weight:
632.13
Formula:
C31H30ClN7O4S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: Reference compound
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