PAD2/4-IN-1 (Compound 4f) is an orally active inhibitor of PAD2 and PAD4 with IC50 values of 23 nM and 10 nM, respectively. PAD2/4-IN-1 can inhibit protein citrullination in neutrophils and reduce hERG channel liabilities. PAD2/4-IN-1 can be used in the research of autoimmune diseases, neurological disorders, and cancers[1].
Molecular Weight:
524.44
Formula:
C26H27Cl2N7O
Target:
Potassium Channel,Protein Arginine Deiminase
Application Notes:
MCE Product type: Reference compound
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