MGB1Y is a noncovalent DNA minor groove binder (MGB). MGB1Y potently inhibits cancer cells proliferation and topoisomerase I activity. MGB1Y downregulates their breast cancer-related genes in MCF7 and MDA-MB-231 cells. MGB1Y has a broad-spectrum anticancer activity, such as breast cancer, colon cancer, and leukemia[1].
Molecular Weight:
603.76
Formula:
C30H33N7O3S2
Target:
DNA Alkylator/Crosslinker,DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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