SMU-C68 is a highly selective small-molecule TLR1/2 heterodimer agonist (EC50=0.009 µM). SMU-C68 activates NF-kappaB and MAPK pathways to promote pro-inflammatory cytokine release (e.g., TNF-alpha, IL-1beta). SMU-C68 is promising for research of cancers[1].
Molecular Weight:
411.54
CAS Number:
[2677039-75-5]
Formula:
C21H21N3O2S2
Target:
NF-kappaB,p38 MAPK,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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