PD-L1/Nampt-IN-1, CAS [[3054043-85-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175294
Supplier Catalog Number:
HY-175294
Alternative Catalog Number:
MCE-HY-175294-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PD-L1/Nampt-IN-1 is an orally active inhibitor that simultaneously target PD-L1 and NAMPT (nicotinamide phosphoribosyltransferase) with IC50s value of 63 nM and 582 nM. PD-L1/Nampt-IN-1 demonstrates cross-species affinity with comparable KD values for hPD-L1 (52.6 nM) and mPD-L1 (49.1 nM), respectively. PD-L1/Nampt-IN-1 effectively inhibits tumor growth by activating the tumor immune microenvironment. PD-L1/Nampt-IN-1 can be used for the study of melanoma[1].
Molecular Weight:
452.55
CAS Number:
[3054043-85-2]
Formula:
C28H28N4O2
Target:
NAMPT,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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