Apoptosis inducer 43 is an apoptosis inducer. Apoptosis inducer 43 can induce apoptosis, SubG0-G1 cell cycle arrest, secondary necrosis, and upregulate caspase-3, p53, and Bax/Bcl-2 expression in HCT116 cells. Apoptosis inducer 43 can inhibit tumor growth in a solid Ehrlich carcinoma (SEC) mouse model. Apoptosis inducer 43 can be used to study cancers such as colon cancer, leukemia, and non-small cell lung cancer[1].
Molecular Weight:
560.56
Formula:
C32H27F3N2O4
Target:
Apoptosis,Bcl-2 Family,Caspase,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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