HIV-1-IN-83 (Compound 18E) is a HIV-1 non-nucleoside reverse transcriptase inhibitor with an IC50 of 0.45 µM for wild-type HIV-1 non-nucleoside reverse transcriptase. HIV-1-IN-83 has potent antiviral activity against both HIV-1 wild-type and mutant strains and improves antidrug resistance for Y188L and RES056 mutant strains. HIV-1-IN-83 has no significant toxicity up to 11.088 µM[1].
Molecular Weight:
668.79
Formula:
C33H32N8O4S2
Target:
HIV,Reverse Transcriptase
Application Notes:
MCE Product type: Reference compound
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