YAP/TEAD-IN-2 (Compound T-1) is a YAP/TEAD inhibitor. YAP/TEAD-IN-2 inhibits the luciferase activity driven by YAP/TEAD in 293T cells. YAP/TEAD-IN-2 exhibits strong anti-proliferative activity against human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 can be used for the study of diseases associated with Hippo pathway dysregulation, particularly cancers[1].
Molecular Weight:
404.42
Purity:
99.00
CAS Number:
[2957895-40-6]
Formula:
C21H20N6O3
Target:
YAP
Application Notes:
MCE Product type: Reference compound
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