QPyN16Th is an N-palmitoylated cationic thiazolidine antibiotic. QPyN16Th is selectively active against the Gram-positive bavteria E. faecalis, S. aureus and MRSA with an MIC of 1.95 µM over gram-negative bacteria. QPyN16Th can induce membrane permeabilization and depolarization and ROS production in MRSA. QPyN16Th increases the survival of zebrafish model of intramuscular MRSA infection[1].
Molecular Weight:
546.59
Formula:
C25H43IN2OS
Target:
Antibiotic,Bacterial
Application Notes:
MCE Product type: Reference compound
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