PROTAC sEH-degrader-3, CAS [[3093413-94-3]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC sEH-degrader-3, CAS [[3093413-94-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-175392
• Supplier Catalog Number: HY-175392
• Alternative Catalog Number: MCE-HY-175392-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC sEH-degrader-3 (Compound 1a) is a targeted sEH PROTAC degrader that can selectively degrade sEH in the cytosol without affecting sEH in peroxisomes. PROTAC sEH-degrader-3 degrades sEH through a CRBN-dependent lysosomal pathway rather than the proteasome, with an IC50 of 0.8 nM against hsEH. PROTAC sEH-degrader-3 can inhibit endoplasmic reticulum stress and can be used in the research of inflammation, metabolic diseases, and other diseases related to endoplasmic reticulum stress. (Pink: sEH inhibitor (HY-114266), Black: Linker (HY-W008352), Blue: E3 Ligase Ligand (HY-14658))[1].

Product Properties

• Molecular Weight: 970.94
• CAS Number: [3093413-94-3]
• Formula: C46H53F3N6O14
• Target: Epoxide Hydrolase,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound