Yoda2 (KC289) is the potassium salt of Yoda1 (HY-18723). Yoda2 is an agonist of PIEZO1 with an EC50 of 150 nM. Yoda2 evokes Ca2+ elevation in HeLa cells. Yoda2 can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50 = 1.2 µM). Yoda2 can stimulate NOS3 and NO production[1].
Molecular Weight:
435.39
Purity:
99.57
CAS Number:
[3081450-95-2]
Formula:
C16H9Cl2KN2O2S2
Target:
NO Synthase,Piezo Channel
Application Notes:
MCE Product type: Reference compound1
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