K-833 is a GPR119 agonist with EC50 values of 39.8 nM (human), 100nM (mouse), 75.4 nM (rat) and 12.6 nM (dog). K-833 demonstrates a modest increase in GLP-1 secretion and leads to a synergistic increase in GLP-1 levels when combined with AM-5262 (HY-16619) in acute gut peptide secretion assays in mice. K-833 can be used in studies on weight loss[1].
Molecular Weight:
640.14
CAS Number:
[2639936-77-7]
Formula:
C30H43ClFN5O7
Target:
GPR119
Application Notes:
MCE Product type: Reference compound1
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