N3-CMC is a click chemistry reagent. N3-CMC containing an azide group can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-CMC can also undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. N3-CMC reacts specifically with the pseudouridine (psi)-containing RNA, and biotin is subsequently conjugated to the N3-CMC-psi RNA via click chemistry, quantitatively analyzing the dynamic changes of psi[1].
Molecular Weight:
464.58
CAS Number:
[1801187-61-0]
Formula:
C21H32N6O4S
Target:
Others
Application Notes:
MCE Product type: Reference compound1
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