SMI-10B13 is an Oncostatin M (OSM) inhibitor with a KD of 6.6 µM. SMI-10B13 inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines (IC50 = 136 and 164 nM, respectively). SMI-10B13 shows anti-tumor effect in human breast cancer mice models[1].
Molecular Weight:
368.38
Purity:
99.30
CAS Number:
[3108487-29-9]
Formula:
C23H16N2O3
Target:
Interleukin Related,STAT
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted