dual FXR/PPARdelta agonist-2 is a FXR/PPARdelta dual agonist through hybridation of FXR agonist GW-4064 and PPARdelta agonist GW-0742.dual FXR/PPARdelta agonist-2 displays potent dual-target activities with a FXR agonistic EC50 of 12.28 nM and 69 % PPARdelta activation at 100 nM. dual FXR/PPARdelta agonist-2 shows anti-fibrotic effects in pulmonary fibrosis mouse model[1].
Molecular Weight:
519.55
Formula:
C26H29N7O5
Target:
FXR,PPAR
Application Notes:
MCE Product type: Reference compound
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