ATX-IN-3 is an orally active autotaxin (ATX) inhibitor with an IC50 of 46 nM. ATX-IN-3 certainly reduces collagen deposition and ameliorates lung fibrosis in the pulmonary fibrosis mouse model. ATX-IN-3 has good metabolic stability and drug-like properties. ATX-IN-3 can used for the study of idiopathic pulmonary fibrosis (IFP)[1].
Molecular Weight:
526.56
Formula:
C29H27FN6O3
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound1
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