Nrf2 activator-21, CAS [[1912404-14-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175548
Supplier Catalog Number:
HY-175548
Alternative Catalog Number:
MCE-HY-175548-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Nrf2 activator-21 is a Nrf2 activator with dual antioxidant and neuroprotective properties. Nrf2 activator-21 binds to Keap1 Kelch domain and disrupts Keap1-Nrf2 interactions and activate antioxidant defense mechanisms. Nrf2 activator-21 reduces apoptosis and decreases caspase-3 activity in the hippocampal neurons. Nrf2 activator-21 targets cerebral ischemia/reperfusion injury (CIRI) via Nrf2 pathway activation. Nrf2 activator-21 improves neurological function, alleviates anxiety-like behavior, enhances memory in rats with 2-vessel occlusion (2VO)-induced CIRI. Nrf2 activator-21 can be used for the study of cerebral ischemia/reperfusion injury[1].
Molecular Weight:
322.31
CAS Number:
[1912404-14-8]
Formula:
C19H14O5
Target:
Apoptosis,Caspase,Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound
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