EGFR-IN-170 (Compound 5c) is an EGFR inhibitor with an IC50 of 5.17 µM. EGFR-IN-170 induces apoptosis by inhibiting Bcl2 expression and activating Bax expression with a significantly increased ratio of Bax/Bcl2. EGFR-IN-170 has potent anticancer activity and inhibits the cell growth of resistant lung cancer cells[1].
Molecular Weight:
585.52
Formula:
C27H27N3O12
Target:
Apoptosis,Bcl-2 Family,EGFR
Application Notes:
MCE Product type: Reference compound
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