Z6466608628 hydrochloride is a selective PPIL4 molecular glue degrader with human PPIL4 EC50 values of 0.34 µM. Z6466608628 hydrochloride functionally recruits PPIL4 to CRBN, induces CRL4CRBN-mediated ubiquitylation and degradation of PPIL4. Z6466608628 hydrochloride can be used for the research of intracranial aneurysms[1].
Molecular Weight:
440.92
Purity:
99.25
Formula:
C23H25ClN4O3
Target:
Molecular Glues
Application Notes:
MCE Product type: Reference compound
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