ALOX5 stabilizer-1 is an arachidonate 5-lipoxygenase (ALOX5) stabilizer with a Kd of 7.26 µM. ALOX5 stabilizer-1 inhibits beta-catenin protein levels and then suppresses STAT3 signal pathway. ALOX5 stabilizer-1 induces lung cancer cells apoptosis, inhibited cell migration and proliferation. ALOX5 stabilizer-1 can used for the study of non-small cell lung cancer (NSCLC)[1].
Molecular Weight:
552.62
Formula:
C32H32N4O5
Target:
Apoptosis,Lipoxygenase,STAT,beta-catenin
Application Notes:
MCE Product type: Reference compound1
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