AZD9750 is an orally active, Cereblon (CRBN)-recruiting, androgen receptor (AR)-targeted PROTAC degrader. AZD9750 induces the proteasome-dependent degradation of both wild-type AR and the drug-resistant mutant ARL702H, thereby inhibiting the AR signaling pathway. AZD9750 suppresses tumor growth in mouse prostate cancer xenograft models and has been utilized in prostate cancer research[1].
Molecular Weight:
758.35
Purity:
98.15
CAS Number:
[3056515-10-4]
Formula:
C43H48ClN9O2
Target:
Adenosine Receptor,PROTACs
Application Notes:
MCE Product type: Reference compound
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