AZD9750 is an orally bioavailable proteolysis-targeting chimera (PROTAC) and androgen receptor (AR) inhibitor.AZD9750 induces proteasome-dependent degradation of wild-type AR and ARL702H resistance mutant, dependent on binding to both AR and cereblon (CRBN).AZD9750 inhibits AR signaling in vitro.AZD9750 inhibits tumor growth in a mouse prostate cancer xenograft model.AZD9750 can be used for the research of prostate cancer[1].
Molecular Weight:
758.35
Purity:
98.15
CAS Number:
[3056515-10-4]
Formula:
C43H48ClN9O2
Target:
Adenosine Receptor,PROTACs
Application Notes:
MCE Product type: Reference compound1
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