MDI-117740 is a dual LIMK1/2 inhibitor. MDI-117740 shows effective cellular target engagement with LIMK1 (pIC50 = 6.73) and LIMK2 (pIC50 = 7.18) in HEK293 cells. MDI-117740 exerts significant anti-migratory activity in MDA-MB-231 cells. MDI-117740 can be used for the study of cancers and neurodegenerative disorders[1].
Molecular Weight:
400.47
Formula:
C24H24N4O2
Target:
LIM Kinase (LIMK)
Application Notes:
MCE Product type: Reference compound
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