JAK2-IN-14, CAS [[3087335-24-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175684
Supplier Catalog Number:
HY-175684
Alternative Catalog Number:
MCE-HY-175684-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
JAK2-IN-14 is an orally active JAK2 inhibitor with an IC50 of 2 nM. JAK2-IN-14 demonstrates 89.5-, 80.5-, and 51-fold selectivity over JAK1, JAK3, and TYK2, respectively. JAK2-IN-14 inhibits STAT5 signaling pathway. JAK2-IN-14 causes tumor cell cycle arrest and apoptosis. JAK2-IN-14 can used for the study of myeloproliferative neoplasms (MPNs)[1].
Molecular Weight:
459.59
CAS Number:
[3087335-24-5]
Formula:
C26H33N7O
Target:
Apoptosis,JAK,STAT
Application Notes:
MCE Product type: Reference compound
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