SRD5A1-IN-2 is a inhibitor of steroid 5alpha-reductase type-1 (SRD5A1), with an IC50 of 8.5 µM. SRD5A1-IN-2 downregulates SRD5A1 protein expression in HaCaT cells. SRD5A1-IN-2 reduces dihydrotestosterone (DHT) production in HaCaT cells. SRD5A1-IN-2 can be used for the study of androgen-related conditions such as androgenetic alopecia (AGA)[1].
Molecular Weight:
406.28
Formula:
C18H12F6O4
Target:
5 alpha Reductase
Application Notes:
MCE Product type: Reference compound
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