SMARCA2/4 degrader-1, CAS [[2901804-87-1]] Preis auf Anfrage

Product Overview

• Article Name: SMARCA2/4 degrader-1, CAS [[2901804-87-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-175756
• Supplier Catalog Number: HY-175756
• Alternative Catalog Number: MCE-HY-175756-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SMARCA2/4 degrader-1 is a SMARCA2/4 molecular glue degrader with a DCAF16 EC50 of 110 nM. SMARCA2/4 degrader-1 covalently adducts at cysteine to form a ternary complex with SMARCA2/4 and recruits CUL4DCAF16 and CRL1FBXO22 E3 ligase complexes. SMARCA2/4 degrader-1 induces ubiquitination and proteasomal degradation of SMARCA2/4. SMARCA2/4 degrader-1 can be used for research of SMARCA4-deficient malignancies, non-small cell lung cancer (NSCLC), and colorectal cancer[1].

Product Properties

• Molecular Weight: 509.65
• CAS Number: [2901804-87-1]
• Formula: C30H35N7O
• Target: Molecular Glues,SWI/SNF Complex

Application Notes

• Application Notes: MCE Product type: Reference compound