SRT6, an anticancer agent is a CD44 inhibitor. SRT6 inhibits key CD44-associated kinases, including SRC, ERBB2 and MAPKAPK2. SRT6 has strong tumor selectivity over non-tumoral lung cells and significant antiproliferative activity against cancer cells (EC50of 1.37 µM for NCI-H23 cells)[1].
Molecular Weight:
514.55
Formula:
C25H26N2O8S
Target:
CD44,EGFR,MAPKAPK2 (MK2),Src
Application Notes:
MCE Product type: Reference compound
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