Ferroptosis inducer-10 is a ferroptosis inducer. Ferroptosis inducer-10 can inhibit A549 cells growth with an IC50 of 0.76 µM. Ferroptosis inducer-10 can deplete GSH, elevate ROS and MDA, and downregulate GPX4 expression. Ferroptosis inducer-10 can induce cell G2/M phase and inhibit migration. Ferroptosis inducer-10 can be used for the research of cancer, such as non-small lung cancer[1].
Molecular Weight:
302.33
Formula:
C19H14N2O2
Target:
Ferroptosis,Glutathione Peroxidase
Application Notes:
MCE Product type: Reference compound
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