APL-1082 (Mc-exo-EVC-Exatecan) is a drug-Linker conjugate that can be used for ADC synthesis. APL-1082 contains Exatecan (HY-13631) and Linker (HY-175929). APL-1082 reduces aggregation and hydrophobicity in Trastuzumab (HY-P9907) ADCs, enables production of high-DAR (10) ADCs with homogeneity and defined physicochemical properties. APL-1082 forms a Trastuzumab ADC with enhanced stability, showing greater DAR retention over time. APL-1082 can be used for the research of gastric cancer[1].
Molecular Weight:
1220.26
CAS Number:
[2921735-93-3]
Formula:
C60H70FN11O16
Target:
Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: Reference compound
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