Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 µM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing[1][2].
Molecular Weight:
663.07
Purity:
98.86
CAS Number:
[57808-65-8]
Formula:
C22H14Cl2I2N2O2
Target:
Parasite
Application Notes:
Reference compound
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