PDE1-IN-10 is a potent and sekective Phosphodiesterase 1 (PDE1) inhibitor with an IC50 of 5 nM. PDE1-IN-10 can suppress TGF-beta/Smad-MAPK signaling and exhibit antifibrotic effects. PDE1-IN-10 can be used for the research of idiopathic pulmonary fibrosis[1].
Molecular Weight:
423.41
Formula:
C24H19F2NO4
Target:
p38 MAPK,Phosphodiesterase (PDE),TGF-beta/Smad
Application Notes:
MCE Product type: Reference compound
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