TRPA1 agonist-3 is a selective and orally active TRPA1 agonist, with EC50 values of 50.05 µM and 314.04 µM for human and mouse TRPA1, respectively. TRPA1 agonist-3 does not activate hTRPV1, mTRPV2, hTRPV3, hTRPV4, hTRPC6, or hTRPM8 channels. TRPA1 agonist-3 alleviates inflammatory pain in mice through a channel desensitization mechanism[1].
Molecular Weight:
262.37
Purity:
99.78
CAS Number:
[3083086-77-2]
Formula:
C14H18N2OS
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound1
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