S1P1 agonist 7 Preis auf Anfrage
Catalog Number:
MCE-HY-175984
| Article Name: |
S1P1 agonist 7 Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-175984 |
| Supplier Catalog Number: |
HY-175984 |
| Alternative Catalog Number: |
MCE-HY-175984-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| S1P1 agonist 7 is a potent, orally active, and beta-arrestin-biased S1P1 agonist (EC50(G-protein) = 12.7 nM and EC50(beta-arrestin) = 3.23 nM). S1P1 agonist 7 demonstrates potent immunomodulatory activity and a favorable safety profile. S1P1 agonist 7 exhibits excellent metabolic stability, minimal to moderate CYP inhibition, and S1P3-sparing selectivity. S1P1 agonist 7 shows pharmacokinetics, effectively reduces circulating lymphocytes, and significantly alleviates disease severity in experimental autoimmune encephalomyelitis (EAE) mouse models under both prophylactic and therapeutic regimens. S1P1 agonist 7 can be used for multiple sclerosis (MS) research[1]. |
| Molecular Weight: |
406.43 |
| Formula: |
C23H22N2O5 |
| Target: |
LPL Receptor |
| Application Notes: |
MCE Product type: Reference compound |
