TRPV1 antagonist 11, CAS [[3084843-71-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-176063
Supplier Catalog Number:
HY-176063
Alternative Catalog Number:
MCE-HY-176063-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
TRPV1 antagonist 11 (compound 2ac) is a potent TRPV1 antagonist with an IC50 of 29.3 nM. TRPV1 antagonist 11 is a potent µ-opioid receptor (MOR) agonist with a Ki of 60.3 nM. TRPV1 antagonist 11, a pyrimidine piperazine, exhibits pain relieving effects by antagonizing TRPV1 and stimulating MOR. TRPV1 antagonist 11 shows a potent, dose-dependent anti-nociceptive effect in a Formalin-induced pain model in mice[1].
Molecular Weight:
539.67
CAS Number:
[3084843-71-7]
Formula:
C31H37N7O2
Target:
Opioid Receptor,TRP Channel
Application Notes:
MCE Product type: Reference compound
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